Buy Deschloroketamine (DCK) For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

What is Deschloroketamine (DCK)

Deschloroketamine (DCK), chemically known as 2-(methylamino)-2-phenylcyclohexanone, is a dissociative anesthetic and an arylcyclohexylamine compound structurally related to ketamine but distinguished by the absence of a chlorine atom on the cyclohexanone ring. It acts as a non-competitive NMDA receptor antagonist, producing effects similar to ketamine such as analgesia, sedation, and dissociation. DCK exists as enantiomers with distinct pharmacological profiles, with the (S)-DCK enantiomer exhibiting greater receptor affinity and activity. It is widely used in preclinical and pharmacological research for studying NMDA receptor-mediated mechanisms, neuroprotection, and behavioral effects. It is exclusively for laboratory research and is not for human or veterinary use.

Technical Information of Deschloroketamine (DCK)

Typical Research Applications of Deschloroketamine (DCK)

Deschloroketamine is commonly applied in neuropharmacological studies exploring NMDA receptor antagonism, neuroprotection, and behavioral paradigms involving dissociative anesthetics. It is used to investigate the cytotoxicity and efficacy differences between its enantiomers and to compare its pharmacodynamics with ketamine. Additionally, DCK serves in research on psychiatric and neurological disorders, substance abuse potential, and receptor binding affinities. Its precise analytical characterization makes it suitable for in vitro and in vivo pharmacokinetic and pharmacodynamic exploration.

Safety and Handling Information for Deschloroketamine (DCK)

Appropriate laboratory safety practices must be observed including the use of personal protective equipment such as gloves and goggles. Handle within well-ventilated environments or chemical fume hoods to avoid inhalation or skin exposure. This compound is for research use only and must not be used for human or veterinary applications. Disposal of residues must comply with institutional chemical safety protocols.

Ordering & Shipping Summary for Deschloroketamine (DCK)

Available exclusively for research institutions and laboratories, Deschloroketamine is shipped under secure packaging with strict adherence to temperature control recommendations to preserve integrity. Purchase requires compliance with applicable regulations regarding research chemicals.

Storage Conditions for Deschloroketamine (DCK)

Store Deschloroketamine in tightly sealed containers at refrigerated temperatures between 2 and 8 °C, avoiding exposure to light and moisture to maintain stability and potency.

Alternatives to Deschloroketamine (DCK)

Alternatives include ketamine and other arylcyclohexylamines like methoxetamine (MXE) or 3-MeO-PCP, depending on the required pharmacological profile of the research.

FAQ About Deschloroketamine (DCK)

Q: What makes Deschloroketamine different from ketamine?
A: It lacks the chlorine atom on the cyclohexanone ring, which alters its pharmacodynamics and receptor affinity.

Q: What are the pharmacological effects of DCK?
A: It produces dissociation, analgesia, and sedation through NMDA receptor antagonism.

Q: What purity can be expected for research-grade DCK?
A: Purity is typically ≥98%, confirmed by HPLC assays.

Q: How should DCK be stored?
A: Store refrigerated at 2–8 °C, protected from light and moisture.

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